InterPro (The Integrated Resource of Protein Domains and Functional Sites)

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InterPro (The Integrated Resource of Protein Domains and Functional Sites)

The family and motif databases, PROSITE, PRINTS, Pfam and ProDom, have been integrated into a powerful resource for protein secondary annotation. As of June 2000, InterPro had processed 384 572 proteins in SWISS-PROT and TrEMBL. Because the contributing databases have different clustering principles and scoring sensitivities, the combined assignments compliment each other for grouping protein f...

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Signature databases are vital tools for identifying distant relationships in novel sequences and hence for inferring protein function. InterPro is an integrated documentation resource for protein families, domains and functional sites, which amalgamates the efforts of the PROSITE, PRINTS, Pfam and ProDom database projects. Each InterPro entry includes a functional description, annotation, liter...

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InterPro: An Integrated Documentation Resource for Protein Families, Domains and Functional Sites

The exponential increase in the submission of nucleotide sequences to the nucleotide sequence database by genome sequencing centres has resulted in a need for rapid, automatic methods for classification of the resulting protein sequences. There are several signature and sequence cluster-based methods for protein classification, each resource having distinct areas of optimum application owing to...

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ژورنال

عنوان ژورنال: Yeast

سال: 2000

ISSN: 0749-503X,1097-0061

DOI: 10.1002/1097-0061(200012)17:4<327::aid-yea45>3.0.co;2-k